General Cell Lines and Cell Cultures
ACROBiosystems Human CCR8 2Vials
This entry represents CC chemokine receptor 8 (CCR8) which it is expressed predominantly in lymphoid tissues and has also been found in glomerular podocytes and human umbilical vein endothelial cells (HUVECs). CCR8 is associated with Th2 lymphocytes which are critical for allergy and has a role in lymphocyte activation migration proliferation and differentiation and in allergic diseases. CCR8 binds to CCL1 (also known as I-309) and to CCL16 (also known as liver expressed chemokine). It also exhibits a high affinity for three chemokines of viral origin: vMIP-I vMIP-II and vMCC-I.
ACROBiosystems FcRn FCGRT B2M 2Vials
FCGRT B2M heterodimer protein (FcRn complex) consist of two subunits p51 (equivalent to FCGRT) and p14 (equivalent to beta-2-microglobulin) and forms an MHC class I-like heterodimer. Fc fragment of IgG receptor transporter alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.
ACROBiosystems Human Mesothelin 2Vials
Mesothelin (MSLN) is also known as CAK1 antigen Pre-pro-megakaryocyte-potentiating factor which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.
ACROBiosystems Human CEACAM-5 2Vials
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is also Carcinoembryonic antigen (CEA) Meconium antigen 100 CD antigen CD66e CEACAM5 belongs to the immunoglobulin superfamily and CEA family. CEACAM5 contains seven Ig-like (immunoglobulin-like) domains. CEACAM5 is homodimer protein which binding of E.coli Dr adhesins leads to dissociation of the homodimer. CEACAM5 is cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. CEACAM5 is receptor for E.coli Dr adhesins.
ATCC CESS; Leukemia; Human (Homo sapiens)
CESS is a lymphoblast cell isolated from the blood of a White male with myelomonocytic leukemia.
ATCC Klebsiella pneumoniae; Strain: KP1074
Klebsiella pneumoniae strain KP1074 [B21] is a whole-genome sequenced bacterium that was isolated from a human with leukemia/lymphoma in Tel-Hashomer, Israel. This strain produces Klebsiella pneumoniae carbapenemase (KPC-3). The depositor states that this strain can be used as a QC reference strain for testing new beta-lactam/beta-lactamase inhibitor combinations such as meropenem/vaborbactam. The bacterium is a CLSI control strain for antimicrobial susceptibility testing.
Charles River Labs Cell Solutions PBMC CRYO 100M
For Research Use Only. Human Normal Peripheral Blood Mononuclear Cells (PBMC) - Cryopreserved, 100 million cells/vial. Mononuclear cells (PBMCs) are purified using density gradient centrifugation techniques.
ATCC NCI-H520; Lung Carcinoma; Human (Homo sapiens)
NCI-H520 [H520] cells were isolated from the lung tissue of a male squamous cell carcinoma patient. Use these cells in your cancer research and as a transfection host.
ATCC Enterovirus A71; Strain: BrCr
Enterovirus A71 strain BrCr is propagated in Vero cells (ATCC CCL-81). This strain was originally isolated from the stool specimen of a 2-month-old male with aseptic meningitis and was derived by passage in Vero cells. It has applications in enteric disease research.
STEMCELL Technologies Human Peripheral Blood Mononuclear Cells, Frozen
Streamline your assays with ready-to-use, ethically sourced, primary human mononuclear cells. With personalized service, flexible delivery times, and the option to reserve entire lots to prescreen cells for applications, we help you get the cells you need. Isolated from peripheral blood leukapheresis samples using density gradient separation and/or red blood cell lysis and cryopreserved in animal component-free CryoStorCS10 medium (Catalog #07930), cells are collected using Institutional Review Board (IRB)-approved consent forms and protocols. Additional documentation and high-resolution HLA typing (Class I and Class II alleles and CMV status) are available upon request. Acid-citrate-dextrose solution A (ACDA) is added during collection as an anticoagulant. Donor specifications (e.g. BMI category, smoking status, ethnicity, etc.) can be requested. Donors are screened for HIV-1, HIV-2, hepatitis B, and hepatitis C.Certain products are only available in select territories.
Biochain Institute Inc FDA Standard Frozen Tissue Array - Human Adult Normal, 2 slides/PK
This FDA Standard Frozen Tissue Array is designed according to published Guidance for Submission of Immunohistochemistry Applications to the FDA. Each FDA Standard Frozen Tissue Array package has either two or four slides which contain 30 different human normal tissue types and 3 donors per tissue type. This product is intended for Research Use Only.
Cell Applications Inc Cryopreserved Aortic Smooth Muscle Cells, Type 2 Diabetes (HAOSMC-T2D), Adult
Cryopreserved Aortic Smooth Muscle Cells, Type 2 Diabetes (HAOSMC-T2D), Adult
Cell Applications Inc Cryopreserved Rat Schwann Cells (RSC), Adult
Cryopreserved Rat Schwann Cells (RSC), Adult